Groundbreaking Study Shows Resilience-Driven Care reduces ER Visits and Hospitalizations by over 85%

Scientific Publications | October 30, 2020

Trellus Health Co-Founders presented groundbreaking research about how Resilience-driven care generated a 90% reduction in emergency department visits and 88% reduction in hospitalizations for patients with inflammatory bowel disease (IBD)

resilience driven care

Research presented in the October 27th plenary presentation of the American College of Gastroenterology (ACG 2020) annual scientific meeting revealed that a personalized program to increase resilience in patients with inflammatory bowel disease (IBD) reduced hospitalizations and emergency room visits by over 80%.

The researchers, led by Principal Investigator and Trellus Health Co-Founder, Laurie Keefer, PhD, Professor of Medicine (Gastroenterology), and Psychiatry, Icahn School of Medicine at Mount Sinai, and inventor of the GRITT (Gaining Resilience Through Transitions) methodology, say the program builds on the principles of positive psychology, which focuses on how people flourish despite obstacles, and supports patients to achieve six key outcomes: optimism, disease acceptance, self-regulation skills, self-efficacy, social support, and resilience.

“GRITT is about providing highly coordinated expert care that is both holistic and personalized. A chronic condition like Crohn’s can be all-encompassing and extremely onerous for the patient to manage alone. The GRITT philosophy is founded on the idea of connection and coordination to support the patient every step of the way,” says Dr. Keefer.

The GRITT approach gives low-resilience patients a personalized “playbook” that is implemented by a team that includes social workers, dietitians, pharmacists, and nurse specialists. Patients are deemed graduates upon reaching a set of established resilience targets.

The GRITT study included 336 patients, who were selected based on their “GRITT Score,” an algorithm developed by the researchers to measure resilience in multiple areas including disease management skills, social support, physical symptom experience, psychological symptom experience, and nutritional status.

Of the study group, 126 patients graduated from the program; the remaining 210 patients served as controls. Graduates of the program experienced a 90 percent reduction in emergency department visits and an 88 percent reduction in hospitalizations, compared to no significant reductions in health care utilization in the control group at 1—year follow up. Their GRITT Scores increased by an average of 33 points, demonstrating improved resilience.

“The study results underline what we see every day in the clinic at the Feinstein IBD Clinical Center: the extraordinary impact of a resilience-driven care coordination program on the lives of our patients. It is cutting-edge, evidence-based, and extremely patient friendly,” says co-author Marla Dubinsky, MD, Trellus Health Co-Founder and Co-Director of the Susan and Leonard Feinstein IBD Clinical Center at Mount Sinai Hospital, and Professor of Pediatrics (Pediatric Gastroenterology), and Medicine (Gastroenterology), at the Icahn School of Medicine at Mount Sinai.

“Trellus Health’s exclusive license to the patent-pending GRITT methodology from Mount Sinai enables us to apply Dr. Keefer’s psychosocial resilience assessment to risk stratify IBD patients and generate personalized care plans to build resilience,” explained Monique Fayad, Trellus Health, CEO. “We are thrilled to be the first company to apply a resilience-driven approach to care delivery and improve outcomes for complex chronic conditions, starting with IBD.”


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